U.S. stock-index futures fell and oil prices climbed Sunday after President Trump declared Iran's response to the latest American peace proposal "totally unacceptable," pushing financial markets into risk-off territory before Monday's open.

Crude surged on fears that a breakdown in negotiations could threaten supply from the region. Equity futures pointed lower across the board, signaling a rough start for Wall Street when trading resumes.

Trump made the remarks Sunday, offering no indication that a new round of talks was imminent. The statement landed after markets had closed for the week, giving investors no immediate avenue to respond before the overnight session.

No date for resumed negotiations has been confirmed. Markets open Monday morning, and traders will be watching for any White House follow-up before the bell.